Established Reference Knowledge Should Remain Distinct From CGI’s Conceptual Models
Science Foundations should separate established reference knowledge from CGI’s proprietary conceptual framework.
Each foundation page should cite high-quality sources, identify the last review date, and avoid product references.
Foundations explain what the broader scientific literature supports. CGI framework pages explain how CGI organizes and interprets that knowledge.
Reference Knowledge
Explain biological concepts and established evidence without introducing product-specific interpretation.
Measurement Context
Clarify what biomarkers, functional outcomes, omics methods, and study designs can actually establish.
Interpretive Restraint
Keep claims proportional to the strength, scope, and maturity of the underlying evidence.
Six Reference Pages to Establish the Scientific Base
These pages should be among the first scientific resources published by CGI. Together, they create a neutral reference layer for later framework, research, and ingredient-science discussions.
Healthspan Versus Lifespan in Companion Dogs
Chronological age, lifespan, healthspan, functional maintenance, quality of life, and why healthspan is a measurable scientific objective.
The Biology of Canine Aging
Cellular maintenance, mitochondria, inflammation, metabolism, microbiome, proteostasis, structural changes, and functional decline.
Measuring Biological Aging
Epigenetic clocks, telomere-related measures, inflammatory markers, metabolomics, proteomics, body condition, activity, imaging, and outcome measures.
Multi-Omics in Companion-Animal Research
What genomics, epigenomics, transcriptomics, proteomics, metabolomics, and microbiome data can and cannot establish.
Nutritional Geroscience
How nutrition may interact with aging-related biological systems without implying disease treatment or guaranteed lifespan extension.
Evidence Hierarchy in Pet Nutrition
Differences among in vitro work, animal models, controlled colony studies, household-dog studies, real-world evidence, randomized studies, and replicated peer-reviewed evidence.
How Each Foundation Page Should Be Built
The value of a foundation page is not how persuasive it sounds. Its value is whether readers can understand the state of knowledge, where that knowledge comes from, and which conclusions remain uncertain.
View Interpretation Principles →Start With Established Biology
Define concepts before discussing hypotheses, interventions, or emerging findings.
Cite High-Quality Sources
Prioritize peer-reviewed literature, authoritative reviews, and primary research relevant to the topic.
Show the Review Date
Readers should be able to see when the scientific content was last reviewed.
State What Evidence Cannot Establish
Limitations should be visible, especially for biomarkers, omics findings, and mechanistic inference.
Keep Product Promotion Out
Foundation pages should remain neutral reference resources rather than commercial interpretation pages.
A Consistent Structure for Every Foundation Article
Definition
Explain the concept in clear scientific language.
Why It Matters
Explain relevance to canine aging or healthspan.
What the Evidence Shows
Summarize the established literature and major observations.
What It Does Not Prove
Make limitations and interpretation boundaries explicit.
References & Review Date
List high-quality sources and the last scientific review date.
Reference Knowledge First. Interpretation Second.
Use the Foundations section as the scientific reference layer, then move to CGI’s Conceptual Framework and Interpretation Principles for structured evidence analysis.